Evaluation of super-disintegrant potential of acid-modified starch derived from <i>Borassus aethiopum</i> (Aracaceae) shoot in paracetamol tablet formulations
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منابع مشابه
Evaluation of Abelmoschus starch as tablet disintegrant
Seed starch (16.0%w/w) obtained from Abelmoschus moschatus Linn. (Malvaceae) was employed as a disintegrant to paracetamol tablets at concentrations of 2.5-10.0% w/w. The granules prepared by wet granulation technique were evaluated for percentage of fines and flow properties. Tablet properties including thickness, content uniformity, average weight and weight variation, hardness, friability, d...
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The disintegrant potential of native starches of five new cassava (Manihot esculenta Crantz.) varieties developed by the Crops Research Institute of Ghana (CRIG) was studied in paracetamol tablet formulations. The yield of the starches ranged from 8.0 to 26.7%. The starches were basic (pH: 8.1-9.9), with satisfactory moisture content (≤15%), swelling capacity (≥20%), ash values (<1%), flow prop...
متن کاملEvaluation of coprocessed disintegrants produced from tapioca starch and mannitol in orally disintegrating paracetamol tablet.
The study evaluated two novel coprocessed excipients (with two methods) as disintegrants in an orally disintegrating paracetamol tablet formulation. The tablets produced were assessed for mechanical properties with the use of friability and tensile strength while the release properties were assessed with wetting time, water absorption ratio, disintegration time and dissolution profile. The resu...
متن کاملEffects of modification and incorporation techniques on disintegrant properties of wheat (Triticum aestivum) starch in metronidazole tablet formulations.
BACKGROUND Natural polymers serve as cheap, non-toxic, biocompatible excipients in drug delivery. OBJECTIVES Starch from wheat (Triticum aestivum) was investigated as a disintegrant in metronidazole tablet formulations in comparison with sodium starch glycolate (SSG), a standard, synthetic but relatively more expensive disintegrant. MATERIAL AND METHODS Native wheat starch (NAS) was modifie...
متن کاملSimultaneous Spectrophotometric Estimation of Valdecoxib and Paracetamol in Tablet Formulations
The validated method was applied for determination of residual solvents in certain film-coated marketed antibiotic formulation of ciprofloxacin, norfloxacin, pefloxacin, and ofloxacin. Twenty tablets each containing 500 mg, 400 mg, 400 mg, and 200 mg of ciprofloxacin, norfloxacin, pefloxacin, and ofloxacin, respectively were accurately weighed separately. The tablets were crushed in a separate ...
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ژورنال
عنوان ژورنال: Tropical Journal of Pharmaceutical Research
سال: 2020
ISSN: 1596-9827,1596-5996
DOI: 10.4314/tjpr.v19i3.1